Antioxidant activity of local Gompang Batu Plants (Lobelia nummularia Lam) in vitro DPPH Method
Authors
Ester Basani Panggabean
Department of Chemistry, Faculty of Mathematics and Natural Sciences, State University of medan, Jl. Williem Iskandar Pasar V Medan Estate, Medan 20221, Indonesia
Murniaty Simorangkir
Department of Chemistry, Faculty of Mathematics and Natural Sciences, State University of medan, Jl. Williem Iskandar Pasar V Medan Estate, Medan 20221, Indonesia
Free radicals are reactive atoms or molecules because they contain unpaired electrons that easily attack body structures, causing various diseases such as cancer, liver, heart and other degenerative diseases. Antioxidants are compounds or molecules that can reduce free radicals. Natural antioxidants are needed to reduce the effects of using synthetic antioxidants. The local plant gompang batu (Lobelia nummularia Lam) is found in Ruhut Bosi Village, Pangaribuan District and has been used by the community as a traditional medicine. This study aims to determine the content of secondary metabolites and antioxidant activity of ethanol extract of gompang batu in vitro using the DPPH (2,2 diphenyl-1-picrylhydrazyl) method. The results of the phytochemical screening test of the gompang batu plant contain secondary metabolites of flavonoids, alkaloids, steroids/terpenoids and saponins. The results of the antioxidant activity test of the ethanol extract of gompang batu obtained an IC50 value of 135,095 ppm (moderate category) and an IC50 value of vitamin C (as a positive control) of 39,390 ppm.
