PROFILE OF HISTOPATHOLOGY OF CERVICAL CANCER TISSUES IN PATIENTS OF THE DR PIRNGADI MEDAN HOSPITAL

Sry Astuty Hasugian, Khairiza Lubis, Hau V Doan

Abstract


Cervical cancer is a malignant neoplasm that happened in the cervical area.  Several types of cervical cancer that usually happens in women such as squamous cell carcinoma (SCC), adenocarcinoma, adenosquamous carcinoma and neuroendocrine carcinoma. Therefore, this study aims to determine a descriptive description of the histopathological profile of cervical cancer tissue from patients that registered in the Anatomical Pathology Laboratory at the DR. Pirngadi Medan Hospital, in the period of 2019. The type of our research is retrospective descriptive with the sampling technique, namely total sampling. The sample used was cervical cancer tissue obtained from the biopsy and surgery on patients who were registered from January 2019 to December 2019, totaling 18 samples. Based on the descriptive histopathological description, we found three types of cervical cancer tissue: squamous cell carcinoma (55.5%), adenocarcinoma (38.8%) and adenosquamous carcinoma (5.5%). The neuroendocrine carcinoma type did not find in this present study. Of three types of these cervical cancer, we got that cervical cancer patients are women aged between 36-72 years, with an average age of 54 years.


Keywords


histopathology, profile, cervical cancer, tissue.

Full Text:

PDF

References


Agustina R. 2015. Peran Derajat Histopatologi dan Stadium Klinis pada Rekurensi Kanker Payudara. Jurnal Kedokteran. 4(7): 129–134.

Arief D, & Rusda, M. 2013. Pasien Kanker Serviks di RSUP H. Adam Malik Medan Tahun 2011. e-Jurnal Fakultas Kedokteran USU. 1(2): 1-4.

Citra I, Dik P, Indra W, Vega K, Meira D, Siti A. 2018. Perbedaan antara ekspresi tumor activating macrohage (TAM∕CD68) dan tumor supresor gene (P16) pada karsinoma sel skuamosa serviks uteri yang residif dan tidak residif di RSUP Dr. Kariadi Semarang. E-Jurnal Media Medika Muda. 3(3) : 1-6.

Dinas Kesehatan Provinsi Sumatera Utara. 2015. Profil Kesehatan Provinsi Sumatera Utara.

Hellweg D, Gisela, Knebel D, Magnus, Trunk, Marcus J. 2006. Color Atlas of Histopathology of the Cervix Uteri. Springer.

Heryani R. 2018. Hubungan Pengetahuan Wanita Terhadap Pemeriksaan PapSmear di Wilayah Puskesmas Garuda Kota Pekanbaru. Jurnal Endurance. 3(3): 596-602.

Kalof A N, Farnaz D, Marisa RN, Esther O, Christopher NO, Kumarasen C. 2012. Protocol for the Examination of Specimens from Patients with Carcinoma of the Uterine Cervix : Based on AJCC/UICC TNM, 7th edition. College of American Phatologists (CAP). Uterine Cervix 3.2.0.0 : 1-19.

Kementerian Kesehatan Republik Indonesia. 2015. Penanggulangan Kanker Payudara dan Kanker Leher Rahim. Peraturan Menteri Kesehatan.

Klatt E. 2009. The internet Phatology Laboratorium for Medical Education. Macon : Mercer University School of Medicine. Diakses pada tanggal 3 Desember 2019.

Kristian E, & Inderiati, D. 2017. Bahan Ajar Teknologi Laboratorium Medis (TLM) : Sitohistoteknologi. Kementerian Kesehatan Republik Indonesia : Badan Pengembangan dan Pemberdayaan Sumber Daya Manusia Kesehatan.

Perkumpulan Obstetri dan Ginekologi Indonesia (POGI). 2006. Standar Pelayanan Medik Obstetri dan Ginekologi. Jakarta: POGI.

Pirog E C. 2017. Cervical Adenocarcinoma: Diagnosis of Human Papillomavirus–Positive and Human Papillomavirus–Negative Tumors. Artikel. 141 : 1653-1667.

Purwanti A, Hadi I, Nurul H. 2014. Hubungan usia dan jumlah paritas terhadap derajat diferensiasi dan stadium pada squamous cell carcinoma serviks di RSUD Abdul Wahab Sjahranie periode 2011-2013. Korepondensi Kedokteran Universitas Mulawarman.

Rasjidi I. 2009. Epidemiologi Kanker Serviks. Indonesian Journal of Cancer. Tangerang : Fakultas Kedokteran Universitas Pelita Harapan. 3(3): 103-108.

Rosai. 2011. Ackerman’s Surgical Pathology. 10th ed. St. Louis, Missouri : Mosby-Year Book Inc.

Schoolland M, Stephen A, Gregory FS. 2002. Adenocarcinoma of the Cervix : Sensitivity of Diagnosis by Cervical Smear and Cytologic Patterns and Pitfalls in 24 Cases. Artikel penelitian NCBI. 96(1) : 5-13.

Suprapto. 2017. Metodologi Penelitian Untuk Karya Ilmiah. Yogyakarta: Gosyen Publishing.

Vinci, L. 2013. Cervical Cytology. http://www.eurocytology.eu/static/eurocytology/TUR/cervical/LP1Content. Diakses pada tanggal 25 Juni 2020.

Wang You-C, Yen-Lin Y, Cung-Wei F., Shih-Yin H. 2018. Primary signet ring cell carcinoma of the cervix: A case report with review of the literature. Taiwanese Journal of Obstetrics & Gynecology. 57 : 862-866.

World Health Organization. 2006. Department of Reproductive Health and Research and Department of Chronic Diseases and Health Promotion. Comprehensive Cervical Cancer Control. World Health Organization Press.

World Health Organization. 2014. Comprehensive Cervical Cancer Control: a Guide to Essential Practice Second Edition. World Health Organization Press.

Yoon A, Seo-Hee K, Ha-Jeong K, Duk-Soo B, Jeong-Won L. 2011. Primary Signet Ring Cell Carcinoma of the Uterine Cervix: A Case Report. Korean J Obstet Gynecol. 54(9) : 570-573




DOI: https://doi.org/10.24114/jbio.v6i3.19607

Article Metrics

Abstract view : 635 times
PDF - 497 times

Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

INDEXING

  

 

 

 

JBIO : Jurnal Biosains (The Journal of Biosciences), Program Studi Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Negeri Medan. ISSN 2443-1230 (print) dan ISSN 2460-6804 (online)

Lisensi Creative Commons
Ciptaan disebarluaskan di bawah Lisensi Creative Commons Atribusi 4.0 Internasional.