GCMS ANALYSIS OF BIOACTIVE COMPOUNDS OF CHINESE BEAT LEAVES (Peperromia pellucida) WITH EXTRACTION APPLICATION USING SOXHLET ATION METHOD

Armansyah Maulana Harahap, Nila Zusmita Wasni, Indra Priawan M

Abstract


Chinese betel leaf (Perperomia pellucida) is generally widely used as a medicinal plant. Many people use Chinese betel leaf as a traditional medicine based on natural ingredients which are believed to be able to treat various diseases with fewer side effects than synthetic drugs. In general, China betel leaf has several secondary metabolites, generally flavonoids, steroids, alkaloids and terpenoids. However, in testing for secondary metabolites, there is still no clear description of the plant parts taken. So this study aims to determine the secondary metabolites in the young leaves of Chinese betel (Peperromia pellucida) by gas chromatography. The results obtained based on the GCMS analysis contained 18 secondary metabolites. Phytol, 2,3-BIS (4-(CA RBOXYMETHYL) PHENYL) BENZO [B] FURAN, and 6-ALLYL-4,5 -DIMETHOXY- 1,3-BENZOD IOXOLE are the 3 highest bioactive com pounds based on the percentage of content.


Keywords


Chinese bettle; Metabolite; GCMS; Leaf

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Altemini A, Lakhssassi N, Baharlouei A, Watson D and Lightfoot D. (2017). Phytochemicals: Extraction, Isolati on, and identification of bioactive compounds from plants extracts. Journal of mdpi plants. 6(42):1-23.Doi:10.3390/plants60400 42

Egwuche RU, Odetola AA and Erukainure. (2011). Preliminary investigation into chemical properties of peperomia pellucida. Research Journal of Phytochemistry. 5(1): 48- 53, 2011. Doi: 10.3923/rjphy to.2011.48-53

Gita RS and Danuji S. (2021). Study of medicinal plant diversity used in Traditional Medicine of Pamekasan district Community. Jurnal Biologi dan Pembelajaran Biologi. 6(1): 11-23.Doi.org/10.32528/bioma.v6 il.4817.

Goodarzi S, Hadijakhoondi A, Yassa N, Khanavi M and Tofighi Z. (2016). New Benzodioxole compounds from the root extract of astrodaucus persicus. Iranian Journal of Pharmaceutical Research. 15(4): 901-906.

Lutfia N and Atun S. (2018). Isolation and Identification of secondary metabolit compounds in etilasetic fraction on mindi leaf. Jurnal Penelitian saintek. 23(2): 95-102.

Napiorkowska M, Cieslak M, Branska JK, Golinska KK and Nawrot. (2019). Synthesis of New Derivatives of Benzofuran as Potential Anticancer agents. Molecules file Article of MDPI. 24, 1529 Molecules 2019.

Nishar B, Sultan A and Rubab S. (2017). Comparison of medicinally impor tants natural products versus synthetic drugs a short commentary. Natural Products chemistry and Research. 6:2, 2017. Doi.10.4172 /2329-6836.1000308.

Nugraha RV, Ridwansyah H, Ghozali M, Khairani AF and Atik N. (2020). Traditional herbal medicine candidates as complementary treate ments for COVID-19: A-Revie of their mechanism pros and cons. Review Article. Evidenced based complementary and alternative medicine. Volume 2020; 1-12. Doi.org/10.1155/2020/2560645.

Pane MH, Rahman AO and Ayudia EI. (2020). Gambaran penggunaan obat herbal pada masyarakat indonesia dan interaksinya terhadap obat konvensional pada tahun 2020. JOMS. 1(1): 40-62.

Restuati, M and Gultom, ES. (2019). Potensi bakteri yang berasosiasi dengan spons asal pulau Ngge (Sibolga) sebagai sumber antibakteri. Jurnal penelitian saintika. 12(2): 98-104.

Silva R, Sousa FBM, Damasceno S, Carvalho N, Silva V, Oliveira FR, Sousa DP, Aragao K, Barbosa A, Freitas R and Medeiros. (2013) Original Article. 1-10. Doi: 10.1111/ fcp.12049

Sholikhah, Eti Nurwening. (2016). Indonesian medicinal plants as sources of secondary metabolites for Pharmaceuticals industry. Journal of Medical Science I. 48(4): 226-239.

Tejada MV, Ferchau IV, Rivero AC, Cornejo RZ et al. (2021). Use of medicinal plants for COVID-19 prevention and respiratory symptom tratment during the pandemic in cusco, Peru: A Cross sectional survey. Research article published on Plos one. 1-18 september 22, 2021. Doi.org/10.1371/journal.pone.0257165

Waty DR, Saputri FC and Mun’im A. (2017). Secondary Metabolites Screening and Acute toxicity test of Peperomia pellucida (L) Kunth Methanolic Extracts. International Journal of Pharm Tech Research. 10(1): 31-38.

World Health Organization (WHO). (2019). WHO Global Report on Traditional and Complementary medicine 2019. ISBN 978-92-4-151543-6.




DOI: https://doi.org/10.24114/jbio.v8i3.33512

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JBIO : Jurnal Biosains (The Journal of Biosciences), Program Studi Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Negeri Medan. ISSN 2443-1230 (print) dan ISSN 2460-6804 (online)

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