GC-MS ANALYSIS OF SECONDARY METABOLITES OF SENGGANI LEAVES (Melastoma malabatrichum L.)
DOI:
https://doi.org/10.24114/jbio.v10i3.62912Keywords:
Screening, Phytochemicals Metabolites secondary, GC-MS, Methanolic extractAbstract
Traditional medicinal plants have long been used and trusted by the community to treat various diseases. The senggani plant is useful for reducing fever (antispiretic), pain reliever (analgesic), urine laxative (diuretic), treating vaginal discharge (leukorrhea), and as a medicine for various types of wounds. This research was conducted using extracts of Melastoma malabatricum (L.) leaves extracted using methanol as a solvent. GC-MS analysis of secondary metabolites of senggani leaves (Melastoma malabatrichum L.) was carried out as a first step to determine the content of active secondary metabolite compounds contained in senggani leaves.The results of this study show that 8 peaks were observed during maximum run time of 40 min. The results revealed that, compounds such as 3-Hexadecyloxycarbonyl-5-(2-hydroxyethyl)-4-methylimidazolium, Melezitose, Thiosulfuric acid, Neophytadiene, 9-Icosyne, Phytol, Hexadecanoic acid dan 9-Octadecenoic acid (Z) were present in the methanolic extract of Melastoma malabatrichum (L.) which can mostly contribute to several therapeutic activities such as antimicrobial.References
Behera, P., & Balaji, S. (2021). The forgotten sugar: A review on multifarious applications of melezitose. Carbohydrate Research, 500, 108248.
Fransiska, A. N., Odhia, F. N., Putri, G. K., Tyasna, P. S., Putri, T. R., &
Nurfadhila, L. (2023). Literature Review: Molecular Docking Aktivitas Senyawa Antioksidan Alami pada Beberapa Tanaman di Indonesia. Jurnal Farmasetis, 12(1), 55-60.
Ganesan, T., Subban, M., Christopher Leslee, D. B., Kuppannan, S. B., & Seedevi, P. (2022). Structural characterization of n-hexadecanoic acid from the leaves of Ipomoea eriocarpa and its antioxidant and antibacterial activities. Biomass Conversion and Biorefinery, 1-12.
Ghazarian, A., & Oppenheimer, S. B. (2014). Microbead analysis of cell binding to immobilized lectin. Part II: Quantitative kinetic profile assay for possible identification of anti-infectivity and anti-cancer reagents. Acta Histochemica, 116(8), 1514-1518.
Harahap, S. N., & Situmorang, N. (2021). Skrining fitokimia dari senyawa metabolit sekunder buah jambu biji merah (Psidium guajava l.). EduMatSains: Jurnal Pendidikan, Matematika Dan Sains, 5(2), 153-164.
Hashem, M. M., Salama, M. M., Mohammed, F. F., Tohamy, A. F., & El Deeb, K. S. (2019). Metabolic profile and hepatoprotective effect of Aeschynomene elaphroxylon (Guill. & Perr.). PloS one, 14(1), e0210576.
Khairani, S., Rahayu, L., Sandhiutami, N. M., Dewi, R. S., &
Rahmawati, I. (2021). Uji efek anti-inflamasi dan analgesik dari rebusan daun bambu kuning (Bambusa vulgaris Schard). Jurnal Ilmu Kefarmasian Indonesia, 19(2), 266-271.
Kusumowati, I. T. D., Melannisa, R., & Prasetyawan, A. (2014). Daya antibakteri ekstrak etanol daun senggani (Melastoma affine D. Don). Biomedika, 6(2).
Minarno, E. B. (2015). Skrining fitokimia dan kandungan total flavanoid pada buah carica pubescens lenne & k. koch di kawasan Bromo, Cangar, dan dataran tinggi Dieng. El-Hayah: Jurnal Biologi, 5(2), 73-82.
Mudaffar, R. A. (2022). Identifikasi Morfologi dan Ekologi Pada Tumbuhan Liar yang Berpotensi Sebagai Sumber Vitamin C. Perbal: Jurnal Pertanian Berkelanjutan, 10(1), 100-111.
Nurhayat, N., Yuliar, Y., & Marpaung, M. P. (2020). Analisis Efek Konsentrasi Ekstrak Etanol Daun Senggani (Melastoma malabathricum L.) sebagai Antibakteri Staphylococcus aureus. Jurnal Kesehatan Poltekkes Kemenkes Ri Pangkalpinang, 8(1), 17-26.
Zhou, Q., Wu, Z., Cheng, X., Zuo, Z., & Fan, C. (2024). Exploring Melezitose as a Potential Therapeutic Agent in Lung Cancer: Inhibitory Effects on Cell Proliferation and EMT-Mediated Signaling in A549 Cells. Pharmacognosy Magazine, 09731296241251545.
Published
Issue
Section
License
Copyright (c) 2025 Muhammad Yusuf Nasution, Marlinda Nilan Sari Rangkuti, Nurbaity Situmorang
This work is licensed under a Creative Commons Attribution 4.0 International License.
For Authors Jurnal Biosains agree to the following terms:
Authors retain copyright and grant the Jurnal Biosains (JBIO) right of first publication with the work simultaneously licensed under a Creative Commons Attribution License (CC BY-SA 4.0) that allows others to share (copy and redistribute the material in any medium or format) and adapt (remix, transform, and build upon the material) the work for any purpose, even commercially with an acknowledgement of the work's authorship and initial publication in JBIO (Jurnal Biosains)
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in JBIO (Jurnal Biosains)
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
