ELECTROCHEMICAL BIOSENSORS BASED ON MOLECULARLY IMPRINTED POLYMERS (MIPS) AND SURFACE PRINTING FOR INFECTIOUS DISEASE DETECTION
Tinjauan Kemajuan Terkini dan Tantangan dalam Pengembangan Biosensor Elektrokimia Berbasis MIP untuk Deteksi Patogen
DOI:
https://doi.org/10.24114/jqca2t05Abstract
Electrochemical biosensors have emerged as promising tools for the diagnosis of infectious diseases due to their high sensitivity, rapid response, and low cost. The use of molecularly imprinted polymers (MIPs) and surface imprinted polymers (SIPs) as robust and selective artificial receptors has gained significant attention. This review summarizes the recognition mechanisms between MIPs/SIPs and various infectious disease biomarkers, including small molecules, microbial toxins, viruses, and bacterial or fungal cells. Different MIP/SIP fabrication techniques such as electropolymerization, coating, and micro-contact imprinting are discussed. The review also highlights clinical applications of MIP/SIP-based biosensors for detecting specific pathogens, such as HPV, HIV, E. coli, and Zika virus. Key challenges such as enhancing sensitivity and selectivity, as well as the future potential of integrating artificial intelligence in biosensor design, are also addressed
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Copyright (c) 2026 Nazwa Hudaiby, Winsyahputra Ritonga
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